QuickView for protein kinase CK2;jsessionid=551184FB315CC66FDD65C4156064DC3A;jsessionid=4C6D2B07345E0E439D889EE4105A29E9 (gene)
- Gene Symbol:
- Csnk2a1
Mus musculus - Full name:
- casein kinase 2, alpha 1 polypeptide
- Synonyms:
- Csnk2a1-rs4, casein kinase II subunit alpha, CK II alpha, casein kinase II, alpha 1 polypeptide, casein kinase II, alpha 1 related sequence 4
- Genomic Location:
- Chr 2: 152052687-152107583
- Description:
-
Casein kinase II is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein. It is involved in various cellular processes, including cell cycle control, apoptosis, and circadian rhythms. The kinase exists as a tetramer and is composed of an alpha, an alpha-prime, and two beta subunits. The alpha subunits contain the cat...
- Orthologs:
- Homo sapiens , Rattus norvegicus , C. elegans , Saccharomyces cerevisiae , Macaca mulatta , Schizosaccharomyces pombe , Bos taurus , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan): -
Predicted Gene Targets for miR-125 , Predicted Gene Targets for miR-186 , Predicted Gene Targets for miR-141 , Predicted Gene Targets for miR-23 , Predicted Gene Targets for miR-30-3p , Predicted Gene Targets for miR-326 , Predicted Gene Targets for miR-329 , Predicted Gene Targets for miR-331 , Predicted Gene Targets for miR-375 , Predicted Gene Targets for miR-411
GO Molecular Function
beta-catenin binding | protein-containing complex binding | protein serine/threonine kinase activity | molecular function regulator | catalytic activity | ribonucleoprotein complex binding | protein N-terminus binding | identical protein binding | protein binding | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | protein phosphatase regulator activity | transferase activity | enzyme regulator activity | kinase activity | phosphatase regulator activity
GO Biological Process
regulation of cell cycle process | regulation of cysteine-type endopeptidase activity | regulation of dephosphorylation | regulation of cellular localization | regulation of localization | regulation of programmed cell death | peptidyl-amino acid modification | negative regulation of cysteine-type endopeptidase activity | negative regulation of cellular process | regulation of phosphatase activity | regulation of protein localization to membrane | positive regulation of protein catabolic process | negative regulation of proteolysis | regulation of chromosome segregation | cellular process | negative regulation of ubiquitin-dependent protein catabolic process | regulation of chromosome separation | negative regulation of apoptotic process | regulation of proteolysis | regulation of cell cycle | positive regulation of nitrogen compound metabolic process | negative regulation of cellular metabolic process | regulation of cellular process | positive regulation of cell growth | regulation of apoptotic process | regulation of metabolic process | negative regulation of cellular protein catabolic process | peptidyl-threonine phosphorylation | regulation of cellular protein localization | positive regulation of protein metabolic process | regulation of cellular protein catabolic process | regulation of cell proliferation | protein serine/threonine kinase activity | negative regulation of metabolic process | protein modification process | macromolecule modification | molecular function regulator | nitrogen compound metabolic process | regulation of signal transduction | negative regulation of catalytic activity | regulation of peptidase activity | phosphorus metabolic process | regulation of catalytic activity | negative regulation of peptidase activity | protein autophosphorylation | regulation of nitrogen compound metabolic process | regulation of cysteine-type endopeptidase activity involved in apoptotic process | negative regulation of cysteine-type endopeptidase activity involved in apoptotic process | regulation of cellular protein metabolic process | phosphorylation | protein phosphorylation | phosphate-containing compound metabolic process | regulation of cellular metabolic process | regulation of protein metabolic process | positive regulation of signal transduction | positive regulation of cell proliferation | protein metabolic process | regulation of growth | regulation of protein dephosphorylation | metabolic process | regulation of protein catabolic process | regulation of protein localization to plasma membrane | negative regulation of programmed cell death | protein kinase activity | organic substance metabolic process | negative regulation of cellular protein metabolic process | protein phosphatase regulator activity | regulation of Wnt signaling pathway | regulation of phosphate metabolic process | negative regulation of protein catabolic process | negative regulation of protein metabolic process | regulation of cell communication | negative regulation of molecular function | positive regulation of growth | cellular protein metabolic process | enzyme regulator activity | regulation of endopeptidase activity | regulation of phosphoprotein phosphatase activity | kinase activity | regulation of cell growth | peptidyl-serine phosphorylation | cellular protein modification process | negative regulation of hydrolase activity | positive regulation of metabolic process | positive regulation of Wnt signaling pathway | cellular metabolic process | regulation of protein localization | regulation of cell death | negative regulation of cell death | regulation of ubiquitin-dependent protein catabolic process | negative regulation of proteolysis involved in cellular protein catabolic process | regulation of cellular component organization | phosphatase regulator activity | positive regulation of signaling | regulation of signaling | negative regulation of endopeptidase activity | macromolecule metabolic process | regulation of phosphorus metabolic process
GO Cellular Component
PcG protein complex | chromosome | intracellular membrane-bounded organelle | catalytic complex | protein kinase CK2 complex | cell | nuclear lumen | nuclear transcriptional repressor complex | cytoplasm | intracellular organelle | protein-containing complex | histone deacetylase complex | nucleoplasm | plasma membrane | chromatin | nuclear chromosome | Sin3 complex | membrane-bounded organelle | transcriptional repressor complex | nucleus | Sin3-type complex | organelle | SWI/SNF superfamily-type complex | NuRD complex | cell periphery | membrane-enclosed lumen | nuclear chromatin | ATPase complex | intracellular | membrane
